The injection generates antibodies, which proceed to flow into within the organisms of the animals with out opposed reactions.
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Scientists from the Autonomous College of Querétaro (UAQ) reported advances in animal testing of the COVID-19 vaccine that they’re creating, which bears the title of QUIVAX 17.4.
Checks carried out on experimental animals, in addition to on goats, sheep and pigs, “have reported antibody titers of 1 in 2 million; nicely above the common ranges of comparable merchandise ”, commented Dr. Teresa García Gasca, rector of the Home of Research.
This vaccine, developed by a group led by Dr. Juan Joel Mosqueda Gualito, generates antibodies, which proceed to flow into within the organisms of animals with out opposed reactions.
To make the injection, the scientists use a recombinant chimeric protein, which takes as a template the protein of the SARS-CoV-2 virus, from which peptides are designed.
Picture: UAQ by way of Fb.
“Every of the peptides are aligned in a sequence that has nothing to do with the unique protein. Then what was executed is to repeat the alignment to offer extra energy to the chimeric protein. The concept is that every peptide generates its personal quantity of antibodies, that every peptide awakens the immune response of the organism individually, which reinforces the impact of the vaccine ”, mentioned García Gasca.
Peptides are a sequence of amino acids linked collectively and amino acids are the essential unit that make up proteins, that are the constructing blocks of the cell.
“In animals that didn’t obtain the vaccine, we will see that none of them raises the antibody titer. However then we take a look at the three doses: 30, 60 and 100 micrograms and we see that for five peptides we now have an important enhance in antibodies, every peptide by itself generates its personal antibody response and this is essential as a result of it signifies that the immune response it may be extra highly effective, extra highly effective. The outcomes of our experiments on animals: goats, sheep and pigs, we see that they don’t current opposed signs, nothing that causes concern; however they do current very excessive antibody titers, a response of two million occasions per unit ”, explains García Gasca.
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